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On November 22, 2003 the Oklahoma rolled into Lubbock, Texas and dismantled the Red Raiders by a final score of 56-25. It was the 12th consecutive victory for the Sooners on the season and helped boost Jason White's Heisman status. The local star, from Tuttle, OK, passed for 394 yards and four scores while Kejuan Jones also produced five touchdowns.
Defensively the Sooners were just as equally impressive. The Red Raiders entered the game with the nation's top-ranked offense but Oklahoma held Texas Tech quarterback B.J. Symons to a season-low 230 passing yards. Oklahoma's defense picked off Tech's record-setting quarterback five times in the game, which helped produce a span of three OU touchdowns in less than two minutes. The highlight for the Oklahoma defense was a 97-yard interception return by Derrick Strait that set up a three-yard touchdown plunge by Jones.
The 2003 Oklahoma Sooners beat their five Big 12 South opponents by an average score of 58-10.