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Heading into the second week of the College Football Playoff Rankings, the committee was tasked with replacing their initial No. 4 team in Ole Miss. With more than a handful of one-loss teams looking to move up, the CFB Nation waited with anticipation for the reveal. The big winner? The Oregon Ducks who slide up into the playoff picture while Auburn remains the best one-loss team in the eyes of the committee.
The Oklahoma Sooners no longer continue to find themselves ranked as the nation's best two-loss team after moving up three places. That title now belongs to Ole Miss. However, the biggest loser of the week was none other than the Georgia Bulldogs who dropped nine spots followed by the Arizona Wildcats who dropped seven spots after a loss.
| Rank | Team | Last week | Week 10 result | Toughest opponent left (per F/+) | If the season ended today ... |
| 1 | Mississippi State (8-0) | 1 | Won 17-10 vs. Arkansas | Ole Miss | Sugar Bowl vs. Oregon |
| 2 | Florida State (8-0) | 2 | Won 42-31 at No. 25 Louisville | Miami | Rose Bowl vs. Auburn |
| 3 | Auburn (7-1) | 3 | Won 35-31 at No. 4 Ole Miss | Alabama | Rose Bowl vs. Florida State |
| 4 | Oregon (8-1) | 5 | Won 45-16 vs. Stanford | Utah | Sugar Bowl vs. Mississippi State |
| 5 | Alabama (7-1) | 6 | Idle | Auburn | Orange Bowl |
| 6 | TCU (7-1) | 7 | Won 31-30 at No. 20 WVU | Kansas State | New Year's bowl |
| 7 | Kansas State (7-1) | 9 | Won 48-14 vs. Oklahoma St. | TCU | New Year's bowl |
| 8 | Michigan State (7-1) | 8 | Idle | Ohio State | New Year's bowl |
| 9 | Arizona State (7-1) | 14 | Won 19-16 vs. No. 17 Utah | Notre Dame | New Year's bowl |
| 10 | Notre Dame (7-1) | 10 | Won 49-39 at Navy | Louisville | New Year's bowl |
| 11 | Ole Miss (7-2) | 4 | Lost 35-31 vs. No. 3 Auburn | Mississippi State | New Year's bowl |
| 12 | Baylor (7-1) | 13 | Won 60-14 vs. Kansas | Oklahoma | |
| 13 | Nebraska (8-1) | 15 | Won 35-14 vs. Purdue | Wisconsin | |
| 14 | Ohio State (7-1) | 16 | Won 55-14 vs. Illinois | Michigan State | |
| 15 | Oklahoma (6-2) | 18 | Won 59-14 at Iowa St. | Baylor | |
| 16 | LSU (7-2) | 19 | Idle | Alabama | |
| 17 | Utah (6-2) | 17 | Lost 19-16 at No. 14 Arizona St. | Oregon | |
| 18 | UCLA (7-2) | 22 | Won 17-7 vs. No. 12 Arizona | USC | |
| 19 | Arizona (6-2) | 12 | Lost 17-7 at No. 22 UCLA | Arizona State | |
| 20 | Georgia (6-2) | 11 | Lost 38-20 vs. Florida | Auburn | |
| 21 | Clemson (6-2) | 21 | Idle | Georgia Tech | Orange Bowl |
| 22 | Duke (7-1) | 24 | Won 51-48 at Pittsburgh | Virginia Tech | |
| 23 | West Virginia (6-3) | 20 | Lost 31-30 vs. No. 7 TCU | Kansas State | |
| 24 | Georgia Tech (7-2) | NR | Won 35-10 vs. Virginia | Clemson | |
| 25 | Wisconsin (6-2) | NR | Won 37-0 at Rutgers | Nebraska |
The SEC still boasts a few top matchups that could potentially effect the final rankings. How will things shake out before it is all said and done in December? Only time will tell!